openchemlib-sqlite

SQLite-backed molecular database for substructure, exact, and similarity search using OpenChemLib (OCL). Current version: 2.0.0, released September 2025. Uses Node.js built-in node:sqlite (requires Node >=22.5). Does not own the molecules table — you provide it. Key differentiator: works alongside your existing table, uses OCL 512-bit fingerprints, supports stereo-insensitive exact search via optional id_code_no_stereo column. Released as needed; mature library with active maintenance.