MRC File I/O Library

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library 1.5.4 ·python
verified May 23, 2026

mrcfile is a pure Python library designed for reading and writing MRC2014 file format data, commonly used in structural biology for image and volume data. It provides a simple API to expose file headers and data as NumPy arrays. The library is actively maintained, with frequent updates to support new Python and NumPy versions, and to enhance features like large file handling and validation.

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