OpenCRAVAT

Tools · 7

• get_annotators Discover which OpenCRAVAT annotators are being run (a curated default set)
• get_annotator_schema Inspect annotator output schemas (field names/types/descriptions)
• annotate_variant Annotate variants by genomic coordinates (chrom/pos/ref/alt). Accepts only GRCh38/hg38 coordinates
• annotate_rsid Annotate variants by dbSNP rsID
• annotate_caid Annotate variants by ClinGen Allele Registry ID (CAid)
• annotate_hgvs Annotate variants by HGVS notation (g./c./p.)
• convert_protein_to_hgvs Convert a protein missense notation (e.g., BRAF V600E) into candidate GRCh38 genomic HGVS changes (via SynVar), which you can then pass to HGVS annotation